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United Therapeutics Senior Research Associate, Cellular Reprogramming in Manchester, New Hampshire

California, US residents click here (https://www.unither.com/docs/UNITHER%20Applicant%20Notice%20-%20%2812-22-23%29%20Final%202.15.24%20Combined%20EN%20and%20French.pdf#page=9) .

The job details are as follows:

What We Do

We build on the strength of our research and development expertise and a distinctive, entrepreneurial culture that encourages diversity, innovation, creativity, sustainability, and, simply, fun. Since inception, our mission has been to find a cure for pulmonary arterial hypertension and other life-threatening diseases. Toward this goal we have successfully gained FDA approval for five medicines, we are always conducting new clinical trials, and we are working to create an unlimited supply of manufactured organs for transplantation.

We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation (PBC). Our public benefit purpose is to provide a brighter future for patients through (a) the development of novel pharmaceutical therapies; and (b) technologies that expand the availability of transplantable organs. At the same time, we seek to provide our shareholders with superior financial performance and our communities with earth-sensitive energy utilization.

Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of “medicines for life”. We continue to research and develop treatments for cardiovascular and pulmonary diseases, and other orphan diseases.

How you’ll contribute

The Senior Research Associate, Cellular Reprogramming will perform cell studies and execute analytical methods to support the production and process development of autologous reprogramming of somatic cells and supplying sufficient iPSC cultures to support internal efforts relating to the differentiation of iPS-derived cells for development of autologous 3D printed tissue engineered organs.

  • Perform and optimize the development of a robust, autologous reprogramming process from circulating cell types

  • Design studies and lead efforts to propagate and characterize newly generated iPSC lines

  • Write and update SOPs and batch records for various reprogramming processes

  • Write and update standard operating procedures for operation and maintenance of laboratory equipment

  • Conduct the technical transfer of assays into the production team or to internal manufacturing, as needed

  • Design cell studies to address technical and scientific challenges to derivation of iPSCs from blood

  • Record and manage use of materials and reagents needed to carry out experiments

  • Meet 1:1 with managers to review results and progress

  • Maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support, and helping identify areas for improvement

  • Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues

  • Record all laboratory data in the in-house data management system(s)

  • Mentor and train junior staff in laboratory processes and procedures as needed

  • Perform other duties as assigned

For this role you will need

Minimum Requirements

  • Bachelor’s Degree in cellular biology, developmental biology, biomedical engineering or related field with 5+ years of experience in a cell biology, developmental biology or biomedical engineering environment with a bachelor's degree or 3+ years of experience in a Cell Biology, Developmental Biology or Biomedical Engineering environment with a master's degree

  • Experience with IPSC culture and/or maintenance

  • Aseptic Technique and mammalian cell culture

  • Knowledge of cell biology

  • Flow Cytometry

Preferred Qualifications

  • Master’s Degree in cellular biology, developmental biology, biomedical engineering or related field

  • Technical expertise in iPSC reprogramming and maintenance of iPS cultures

  • Technical expertise in maintenance of iPS cultures

  • Ability to initiate and manage day-to-day tasks effectively, including multi-tasking, flexibility and adaptability

  • Ability to independently follow experimental methods and protocols

  • Comfortable working in a hands-on laboratory environment and have good attention to detail and good lab practices

At United Therapeutics, you’ll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged... all while making a difference in the lives of our patients.

While United Therapeutics does not require vaccination for Covid-19 at this time, we strongly encourage all employees and visitors to remain up to date on vaccinations and boosters to protect one another from illness. Employees working in customer-facing roles must adhere and comply with customers’ credentialing guidelines, which may require vaccination against Covid -19, the influenza virus, and other illnesses that could be harmful to healthcare staff and patients.

United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities

We strive to be an organization that engages the minds, hearts, and most spirited efforts of each of our employees. Our sense of purpose transforms what we do from work into mission, occupation into vocation and achievement into success.

We challenge our employees with innovative and revolutionary projects, offer an environment which fosters high-level job performance and provide a highly competitive total rewards package. This is what makes United Therapeutics a stimulating place to work.

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